Richard E Lee Selected Research

Spectinomycin (Spectinomycin Hydrochloride)

1/2019	Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice.
1/2019	Efficacy of Aminomethyl Spectinomycins against Complex Upper Respiratory Tract Bacterial Infections.
1/2018	Aminomethyl Spectinomycins as Therapeutics for Drug-Resistant Gonorrhea and Chlamydia Coinfections.
2/2014	Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux.

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Richard E Lee Research Topics

Disease

32	Tuberculosis (Tuberculoses) 01/2022 - 03/2003
26	Dehydration (Water Stress) 01/2021 - 11/2005
19	Infections 02/2022 - 06/2005
4	Neoplasms (Cancer) 10/2020 - 11/2003
4	Bacterial Infections (Bacterial Infection) 01/2019 - 06/2013
4	Persistent Infection 01/2017 - 01/2011
4	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2017 - 01/2016
4	Buruli Ulcer 06/2005 - 02/2003
3	Hypoxia (Hypoxemia) 11/2018 - 11/2007
2	Neuroblastoma 01/2020 - 06/2006
2	Sepsis (Septicemia) 01/2018 - 05/2015
2	Mycoses (Diseases, Fungus) 01/2017 - 06/2005
2	Water Intoxication 08/2011 - 05/2009
2	Diarrhea 08/2004 - 06/2004
2	Glioma (Gliomas) 08/2004 - 11/2003
1	Inflammation (Inflammations) 10/2022
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2021
1	Propionic Acidemia 09/2021
1	Metabolic Diseases (Metabolic Disease) 09/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2021
1	Carcinogenesis 10/2020
1	Melanoma (Melanoma, Malignant) 10/2020
1	Otitis Media 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Otitis 01/2019
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2019
1	Weight Gain 10/2018
1	Weight Loss (Weight Reduction) 10/2018
1	Immune System Diseases (Immune Disorders) 01/2018
1	Coinfection 01/2018
1	Gonorrhea 01/2018
1	Heart Failure 01/2018
1	Bacteremia 01/2017
1	Leukemia 01/2017
1	Acute Kidney Injury (Acute Renal Failure) 10/2016
1	Chronic Renal Insufficiency 10/2016

Drug/Important Bio-Agent (IBA)

29	Pharmaceutical PreparationsIBA 02/2022 - 06/2004
19	Anti-Bacterial Agents (Antibiotics)IBA 02/2022 - 09/2006
16	Proteins (Proteins, Gene)FDA Link 12/2021 - 08/2004
9	Urea (Carbamide)FDA LinkGeneric 12/2014 - 11/2005
7	EnzymesIBA 01/2020 - 08/2004
6	TrehaloseIBA 02/2015 - 07/2007
5	Biological ProductsIBA 01/2020 - 11/2003
4	Spectinomycin (Spectinomycin Hydrochloride)FDA Link 01/2019 - 02/2014
4	Antitubercular AgentsIBA 01/2017 - 02/2009
4	Glucose (Dextrose)FDA LinkGeneric 02/2015 - 09/2006
4	Irinotecan (Camptosar)FDA LinkGeneric 06/2006 - 11/2003
3	IceIBA 09/2008 - 09/2006
3	mycolactoneIBA 06/2005 - 01/2004
3	MacrolidesIBA 06/2005 - 02/2003
2	Peptides (Polypeptides)IBA 01/2022 - 01/2011
2	Coenzyme A (CoA)IBA 09/2021 - 10/2018
2	Aquaporins (Water Channels)IBA 01/2021 - 08/2015
2	UbiquitinIBA 10/2020 - 12/2012
2	Type II Fatty Acid SynthaseIBA 01/2020 - 02/2015
2	Antineoplastic Agents (Antineoplastics)IBA 01/2020 - 06/2004
2	Messenger RNA (mRNA)IBA 01/2019 - 08/2012
2	ProdrugsIBA 02/2015 - 06/2006
2	Glycerol (Glycerine)FDA LinkGeneric 02/2015 - 07/2007
2	Mycolic Acids (Mycolic Acid)IBA 01/2014 - 02/2012
2	LipidsIBA 01/2014 - 04/2012
2	GlycogenIBA 09/2013 - 04/2012
2	Epoxide HydrolasesIBA 05/2012 - 09/2011
2	Ethambutol (Myambutol)FDA LinkGeneric 03/2008 - 03/2003
2	Lactic Acid (Lactate)FDA LinkGeneric 09/2006 - 05/2005
2	mycolactone AIBA 06/2005 - 02/2003
2	Carboxylesterase (Hydrolase S)IBA 08/2004 - 06/2004
2	PolyketidesIBA 01/2004 - 02/2003
1	ChemokinesIBA 10/2022
1	Interleukin-8 (Interleukin 8)IBA 10/2022
1	Carrier Proteins (Binding Protein)IBA 01/2022
1	snake venom protein C activatorIBA 12/2021
1	pantothenate kinaseIBA 09/2021
1	propionyl-coenzyme A (propionyl-CoA)IBA 09/2021
1	BuffersIBA 11/2020
1	Ligases (Synthetase)IBA 10/2020
1	AntigensIBA 10/2020
1	Hydro-Lyases (Dehydratases)IBA 01/2020
1	Cytotoxins (Cytolysins)IBA 01/2020
1	hydrazine (hydrazine dihydrochloride)IBA 01/2019
1	Isoniazid (Ftivazide)FDA LinkGeneric 01/2019
1	Vitamin B 6IBA 01/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2018
1	NitritesIBA 11/2018
1	NitratesIBA 11/2018
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2018
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2018
1	Gentamicins (Gentamicin)FDA LinkGeneric 01/2018
1	Ampicillin (Omnipen)FDA LinkGeneric 01/2018
1	Vancomycin FDA LinkGeneric 01/2017
1	Drug CombinationsIBA 01/2017
1	Fungal ProteinsIBA 01/2017
1	Anti-Infective Agents (Microbicides)IBA 01/2017
1	AerosolsIBA 01/2017
1	NifurtimoxIBA 04/2016

Therapy/Procedure

16	Therapeutics 10/2021 - 10/2004
6	Fluid Therapy (Oral Rehydration Therapy) 08/2015 - 05/2009
5	Drug Therapy (Chemotherapy) 01/2020 - 03/2003
1	Contraception (Birth Control) 01/2018
1	Percutaneous Coronary Intervention 10/2016